Since Biolux was founded in 2007, research and collaboration with experienced researchers has been embedded in our DNA.
An exclusive collaboration signed with an INSERM team based at the Institute for Neurosciences of Montpellier (INM) allowed Biolux to understand photomodulation’s action mechanism.
Our R&D team’s multidisciplinary expertise has enabled us to validate our treatments’ effectiveness on various levels.
Biolux’s medical progress started with foundational research followed by translational and clinical research to make this technology available for humans.
Research and development on photomodulation research programmes were based on four focus areas, around which all protocols were developed:
Healing – Inflammation – Regeneration – Pain
In Vitro Level
Various tests highlighted the role photomodulation played in cell migration, proliferation and differentiation, as well as in regulating inflammation.
Validation de l’action des LEDs sur la vitesse de pousse neuritique des neurones sensoriels (Validating LED Action on Speed of Neurite Growth in Sensory Neurons): in axotomic conditions, the rate of neuritic growth obtained after an LED stimulation reached a threshold never equalled in the articles available in the literature.
In Vivo Level
The transition before applying clinical stimulation protocols. The tests carried out on more integrated models validated the various results obtained on the cellular level.
Knowledge and technology transferred to therapeutic application. Professional devices and home care models were created for clinical use.
An international clinical study was conducted in partnership with a Brazilian team to evaluate the effect photomodulation has on scars from abdominal plastic surgery. This study definitively validated Biolux technology’s effect on the four research focus areas, all involved in the post-surgical healing process.
Biolux continues to invest in R&D because we are committed to continuous improvement and exploring innovative therapeutic possibilities. We do this by:
Photomodulation’s strong therapeutic potential has led to numerous publications covering a wide range of applications.
Foundamental Research (Partial List)
Clinicals investigations (partial list)
Yoo KH et al. (2015) Efficacy of combination light-emitting diode (635 and 830 nm) therapy in treating local injection-site reactions after filler ; Clin Exp Dermatol. 2015 Apr;40(3):333-5. doi: 10.1111/ced.12480. Epub 2014 Sep 30.
Calderhead RG et al. (2015) Adjunctive 830 nm light-emitting diode therapy can improve the results following aesthetic procedures ; Laser Ther. 2015 Dec 30;24(4):277-89. doi: 10.5978/islsm.15-OR-17.
Oh IY (2013) Efficacy of light-emitting diode photomodulation in reducing erythema after fractional carbon dioxide laser resurfacing: a pilot study ; Dermatol Surg. 2013 Aug;39(8):1171-6. doi: 10.1111/dsu.12213. Epub 2013 Apr 3.
Lee, S. Y., K. H. Park, et al. (2007). A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings ; J Photochem Photobiol B 88(1): 51-67.